Methotrexate side effects

2 min read

Methotrexate is a medication commonly used to treat various medical conditions, including cancer, autoimmune diseases, and severe psoriasis. However, it can have toxic effects on the body, and in cases of methotrexate overdose or severe toxicity, it is helpful for you to have a methotrexate antidote and supportive treatments available.

Chest angina, a condition characterized by chest pain due to reduced blood flow to the heart muscle, is sometimes associated with the use of methotrexate. In such cases, it becomes even more critical to have appropriate methotrexate antidotes and medical interventions at hand to counter the effects of methotrexate toxicity.

The primary antidote used to counteract the toxic effects of methotrexate is folinic acid (leucovorin). Folinic acid, a form of vitamin B9, helps rescue normal cells from the harmful impact of methotrexate while not affecting the cancer cells or cells responsible for the autoimmune disease. This antidote is administered by your healthcare professional, and the dosage and frequency depend on the specific situation and the patient's condition.

In cases of methotrexate toxicity associated with chest angina, immediate medical attention is vital. Healthcare providers, experienced in managing methotrexate-related issues, will administer the antidote, such as folinic acid, as part of a comprehensive treatment plan. This plan may also include other supportive measures like addressing chest angina symptoms, hydration, and monitoring for potential complications.

For more information about methotrexate antidote you can visit Medical Antidote post Methotrexate Antidote: A Critical Intervention

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MOSES MUSYOKI 2
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